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Director: Meenakshi Bidwa Bhattacharjee, M.D., B.S.
Email: mbb@bcm.tmc.edu
Phone: 832-824-1872 |
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The main objective of the Neuropathology core
is to provide BCM-IDDRC investigators with facilities and expertise for the characterization
of tissues from human samples and animal models. Services include histology, histochemistry,
immunohistochemistry, and interpretation of anatomical and histopathological findings.
The Neuropathologist and Core technicians are available to the BCM-IDDRC investigators and
their trainees for instruction in all of the techniques, and in the interpretation of the studies. In some cases the trainee will, under this supervision, develop the techniques in their own laboratory. The objective of the Neuropathology
The Baylor IDDRC consists of researchers working within various areas
of expertise, in which human and animal tissues are investigated in
order to characterize molecular, chemical and morphologic markers. The
morphologic studies include the demonstration of gene products within
cells, identification of specific cell types, histochemical identification
of enzyme activity, ultrastructural characterization of cell organelles,
confirmation of the presence of pathognomonic lesions in human and animal
study subjects, and the identification of the presence or absence of
structural integrity of the nervous system in transgenic and mutant
animal models of human disease. The Neuropathology core provides support
for these necessary studies. Careful neuropathologic and immuno- localization
analyses IDD and the function of neuronal and developmental genes.
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